Faculty Directory
Xi Chen

Assistant Professor of Biomedical Engineering (beginning on June 1, 2025)

Contact

2145 Sheridan Road
Tech
Evanston, IL 60208-3109

Email Xi Chen

Website

Xdeep Intelligent Quantitative Imagine (XIQI)

Departments

Biomedical Engineering

Education

     NIH K99/R00 Postdoc, Mong Fellow, Cornell University, Ithaca, NY

     Postdoc, University of Illinois at Urbana-Champaign, Urbana, IL

     Ph.D. in Physics, University of Miami, Miami, FL

     B.S. in Applied Physics, Chongqing University, Chongqing, China


Research Interests

Our group focuses on developing AI-enhanced optical imaging techniques for quantitative measurement and analysis of complex living systems, ranging from cellular cultures, organoids, deep tissues, to live animals. We design innovative optical systems and computational algorithms that integrate Quantitative Phase Imaging (QPI), multiphoton imaging, adaptive optics, and AI, to deliver customized solutions for investigating pathological processes, conducting high-content phenotypic screening, and performing in vivo target validation.

Selected Publications

X. Chen, M. Kandel, S. He, C. Hu, Y. Lee, K. Sullivan, G. Tracy, H. Chung, H. Kong, M. Anastasio, G. Popescu, Artificial confocal microscopy for deep label-free imaging, Nature Photonics, 1-9. (2023).

X. Chen, M. Kandel, and G. Popescu, Spatial light interference microscopy (SLIM): principle and applications to biomedicine. Advances in Optics and Photonics 13.2, p. 353-425. (2021).

X. Chen, M. Kandel, C. Hu, Y. Lee, and G. Popescu, Wolf phase tomography (WPT) of transparent structures using partially coherent illumination. Light: Science & Applications, 9(1): p. 142. (2020).

X. Chen, O. Korotkova. Phase structuring of 2D complex coherence states. Optics Letters. Vol. 44, Issue 10, pp. 2470-2473 (2019).

X. Chen, J. Li, S. Hashemi, and O. Korotkova, Synthesis of Im-Bessel correlated beam via coherent modes. Optics Letters. Vol. 43, Issue 15, pp. 3590-3593 (2018).

X. Chen and O. Korotkova, Probability density functions of instantaneous Stokes parameters on weak scattering. Optics Communications 400, 1-8 (2017).

Positions:

Our lab is actively recruiting students and postdocs. NIH-funded positions are available. Please check the lab website for more information.