Faculty Directory
Samuel Stupp

Board of Trustees Professor of Materials Science and Engineering, Chemistry, Medicine and Biomedical Engineering and (by courtesy) Biomedical Engineering

Director, Center for Regenerative Nanomedicine

Director, Center for Bio-Inspired Energy Science

Contact

2220 Campus Drive
Cook Hall 2036; Office - Cook 1127
Evanston, IL 60208

Email Samuel Stupp

Website

The Stupp Laboratory

Centers

Center for Regenerative Nanomedicine

Center for Bio-Inspired Energy Science

Departments

Materials Science and Engineering

Biomedical Engineering

Education

Ph.D. Materials Science and Engineering, Northwestern University, Evanston, IL

B.S. Chemistry, University of California at Los Angeles, Los Angeles, CA

Research Interests

Research in the Stupp group integrates chemistry with materials science, biology, and medicine. The overarching interest of the group is the development of self-assembling organic materials, focusing on functions relevant to energy and medicine. In the area of energy science, the laboratory’s interests include materials for solar photovoltaics, catalytic materials that can synthesize solar fuels, supramolecular ferroelectrics for non-volatile memories, and artificial muscle materials for inter-conversion of chemical and mechanical energy. In the area of medicine, the Stupp laboratory focuses on biomaterials for regenerative medicine of the brain, spinal cord, bone, cartilage and muscle, and also on targeted systemic drug delivery using nanostructures for cancer and cardiovascular applications. The organic structures of interest in both areas include visible-light-absorbing chromophores, organometallic catalysts, electron donors and acceptors, DNA, peptides, glycopeptides, and polymers, among others. The group is organized into three subgroups that meet weekly to discuss progress: Energy Materials, Biomaterials, and Supramolecular Self-Assembly. Research activities include molecular synthesis and characterization of structure with a broad suite of microscopies and synchrotron X-ray scattering, measurement of materials properties, computer simulations, construction of solar cells and other electronic devices, molecular and cell biology, and in vivo studies of the efficacy of materials and nanostructures in biomedical applications.

Significant Recognition

Member, National Academy of Sciences (2020)
Nanoscience Prize, International Society for Nanoscale Science, Computation, and Engineering (2020)
Listed in Top 1% Highly Cited Researchers, Web of Science Group (2019)
Fellow, National Academy of Inventors (2018)
Most Cited Researchers in Materials Science & Engineering, Elsevier Scopus Data (2016)
Fellow, Royal Society of Chemistry (2016)
Royal Society of Chemistry Soft Matter and Biophysical Chemistry Award (2016)
Elected to American Institute for Medical and Biological Engineering College of Fellows (2016)
Member, Royal Spanish Academy of Engineering (2015)
Visiting Professor, School of Materials Science and Engineering, Nanyang Technological University, Singapore (2015)
Thomson Reuters The World's Most Influential Scientific Minds (2014)
International Award, The Society of Polymer Science, Japan (2014)
President, International Scientific Committee of the Institute for Bioengineering of Catalonia, Spain (2014)
Distinguished Visiting Scientist of the Institute of Materials Research and Engineering, Singapore (2014)
Distinguished Visiting Professor of Biochemistry, University of Hong Kong (2014)
Creation of the Samuel I. Stupp Prize in Nanotechnology by the Ministry of Science and Technology, Government of Costa Rica (2013)
Honorary Doctorate from the University of Gothenburg, Sweden Medical School (2013)
Australian Centre for Nanomedicine Annual Visiting Professorship (2013)
American Chemical Society Ronald Breslow Award for Achievement in Biomimetic Chemistry (2012)
Member, National Academy of Engineering (2012)
Member, Royal Spanish Academy of Pharmacy (2012)
Honorary Doctorate, National University of Costa Rica (2011)
Thomson Reuters Top 100 Chemists for 2000-2010 (2011)
Fellow, Materials Research Society (2009)
Distinguished Professorship, Eindhoven University of Technology (2009)
Israel Pollack Distinguished Lecture Series Award, Technion-Israel Institute of Technology (2009)
Honorary Doctorate for Revolutionary Research in Complex Molecular Systems, Eindhoven University of Technology (2009)
American Chemical Society Award in Polymer Chemistry (2005)
Fellow, World Technology Network (2003)
Materials Research Society Medal Award (2000)
Humboldt Award for Senior U.S. Scientists (1997)
Joliot Curie Professorship, Ecole Supérieure de Physique et de Chimie Industrielles (1997)
U.S. Department of Energy Prize for Outstanding Scientific Accomplishment in Materials Chemistry (1991)
Xerox Faculty Award for Excellence in Engineering Research (1985)
3M Young Faculty Award (1981)
3M Young Faculty Award (1981)
3M Young Faculty Award (1981)

Significant Professional Service

Member, Executive Advisory Board, Giant (2020)
Member, External Executive Committee (EEC) of CUNY Advanced Science Research Center (ASRC) Nanoscience Initiative, New York, NY (2016)
Member, Advisory Board, Indian Association of Nanoscience and Nanotechnology (IANN), India (2016)
Organizer and Co-Chair of the Inter-Agency Materials Genome Initiative Soft Matter Summit, Washington DC (2013)
Member, RIKEN Center for Emergent Matter Science Advisory Council, Japan (2013)
Member, Scientific Advisory Board, Xeltis Corporation, Zurich, Switzerland (2013)
Co-Chair, Gordon Research Conference on Self-Assembly & Supramolecular Chemistry in Les Diablerets, Switzerland (2013)
Honorary Membership, Israel Chemical Society (2009)
Member, World Premier International Program Advisory Committee to Advanced Institute for Materials Research, Japan Society for the Promotion of Science, Japan (2008)
International Advisory Group, Swedish Government Program on Biomaterials, Gothenburg University (2008)
Member, Scientific Advisory Board, University of Vienna (2006)
Merck-Karl Pfister Visiting Professorship, Massachusetts Institute of Technology (2004)
Member, Scientific Advisory Board, National University of Singapore (2003)
Member, Baxter Scientific Advisory Board (2001)
Member, Solid State Sciences Committee, National Academy of Sciences (2001)
Member, Basic Energy Sciences Advisory Committee, Department of Energy (1999)
Elected member of American Academy of Arts and Sciences (1998)
Fellow of American Association for the Advancement of Science (1999)
Member, Materials Panel, Air Force Scientific Advisory Board (1995)
Exclusive consultant to 3M Company (1987)

Selected Publications

Dannenhoffer, A.; Sai, H.; Bruckner E.P.; Ðorđević, L.; Narayanan, A.; Yang, Y.; Ma, X.; Palmer L.C.; Stupp S.I. “Metallurgical Alloy Approach to Two-Dimensional Supramolecular Materials” Chem 2023, 9(1), 170-180.

Alvarez, Z; Ortega, J. A.; Sato, K.; Sasselli, I. R; Edelbrock, A. N.; Quinlan, K. A.; Mussumeci, C.; Stupp, S. I.; Kiskinis, E. “Artificial Extracellular Matrix Scaffolds of Mobile Molecules Enhance Maturation of Human Stem Cell-Derived Neurons” Cell Stem Cell 2023,

Yamaura, K.; Sather N.A.; Metlushko, A.; Nishimura, H.; Pavlović, R.; Hambright, S.; Kumar Ravuri, S.; Philippon, M.J.; Stupp, S.I.; Bahney, C.; Huard, J. “Sustained-release losartan from peptide nanofibers promotes chondrogenesis” Frontiers in Bioengineering and Biotechnology 2023, 11, 2296-4185.

Kolberg-Edelbrock, J; Cotey, T.J.; Ma, S.Y.; Kapsalis, L.M.; Bondoc, D.M.; Kolberg-Edelbrock, A.N.; Stupp, S.I. “Biomimetic Extracellular Scaffolds by Microfluidic Superstructuring of Nanofibers” ACS Biomaterials Science and Engineering 2023, 9(3) 1251-1260.

Đorđević, L.; Sai, H, Sather, N.A.; Yang, Y.; Palmer, L.C.; Stupp, S.I. “Heterocyclic Chromophore Amphiphiles and their Supramolecular Polymerization” Angewandte Chemie Int. Ed. 2023, e202214997, https://doi.org/10.1002/anie.202214997.

Pavlović, R. Z.; Egner, S.A.; Palmer, L.C.; Stupp. S.I. “Supramolecular Polymers: Dynamic Assemblies of “Dancing” Monomers” Journal of Polymer Science 2023, 61, 870–880.

Li, C.; Kazem-Rostami, M.; Seale, J.; Zhou, S.; Stupp, S.I. “Macroscopic Actuation of Bisazo Hydrogels Driven by Molecular Photoisomerization" Chemistry of Materials 2023, https://doi.org/10.1021/acs.chemmater.3c00062.

Duan, J; Shabbir, H; Chen, Z; Bi, W; Liu, Q; Sui, J ; Đorđević, L; Stupp, S.I.; Chapman, K; Martinson, A; Li, A; Goswami, S; Getman, R ; Hupp, J. “Synthetic access to a framework-stabilized and fully sulfided analogue of an Anderson polyoxometalate that is catalytically competent for reduction reactions” Journal of the American Chemical Society 2023, 145, 13, 7268–7277.

Li, C.; Xiong, Q.; Clemmons, T.; Sai, H.; Yang, Y.; Sangji, M.H.; Iscen, A.; Palmer, L.C.; Schatz, G.C.; Stupp, S.I. “Role of Supramolecular Polymers in Photo-actuation of Spiropyran Hydrogels” Chemical Science. 2023, DOI: 10.1039/D3SC00401E.

Qiu, R; Chen, F; Alvarez, Z; Clemons, T; Biswas, S; Karver, M.; Takata, N; Sai, H; Peng, H; Weigand, S; Palmer, L.C.; Stupp, S.I. "Supramolecular Nanofibers Block SARS-CoV-2 Entry into Human Host Cells" ACS Applied Materials & Interfaces 2023, 15 (22), 26340-26348PMCID #PMC10237298.

Yang, Y.; Li, C.; Palmer, L.C.; Stupp, S.I. “Autonomous Hydrogel Locomotion Regulated by Light and Electric Fields” Science Advances 2023, 9 (31), eadi4566

Smith, C. S.; Álvarez, Z.; Qui, R.; Sasseli, I.; Clemons, T.; Ortega, J.A.; Viliela-Picos, M.; Wellman, H.; Kiskinis, E.; Stupp, S.I. “Enhanced Neuron Growth and Electrical Activity by a Supramolecular Netrin-1 Mimetic Nanofiber” ACS Nano 2023, https://doi.org/10.1021/acsnano.3c04572 .

Pavlović, R.Z.; Finnegan, T. J.; Metlushko, A.; Hansen, A. L.; Waudby, C. A.; Wang, X.; Hoefer, N.; McComb, D. W.; Pavic, A.; Plackic, N.; Novakovic, J.; Bradic, J.; Jeremic, N.; Jakovljevic, V.; Smit, B.; Matic, S.; Alvarez-Saavedra, M. A., Capo, I.; Moore, C. E.; Stupp, S. I. “Dynamic and Assembly Characteristics of Deep‐Cavity Basket Acting as a Host for Inclusion Complexation of Mitoxantrone in Biotic and Abiotic Systems" Chemistry : a European Journal 2023 https://doi.org/10.1002/chem.202303374

Ortega, J. A; Sasselli, I. R.; Boccitto, M.; Fleming, A. C.; Fortuna, T.; Li, Y.; Sato, K.; Clemons, T. D.; McKenna, E.; Nguyen, T. P.; Anderson, E.; Ichida, J.; Pandey, U.; Wolin, S.; Stupp, S. I.; Kiskinis, E. “CLIP-Seq Analysis Enables the Design of Ribosomal RNA Bait Oligonucleotides That Protect Against C9ORF72 ALS/FTD-Associated Poly-GR Pathophysiology” Science Advances 2023, 9(43).

Stone, E.B.S; Đorđević, L.; Stupp, S.I.; Weiss, E.A.; Arcudi, F.; Hupp, J.T. “Selective Photocatalytic Reduction of Acetylene to Ethylene Powered by a Cobalt-Porphyrin Metal–Organic Framework” ACS Energy Letters 2023, 8(11), 4684–4693.

Zhou,Y.; Fyrner, T; Chen. C; Sather, N.; Hsu, E.; Stupp, S.I. “Optimization of peptide amphiphile-lipid raft interaction by changing PA lipophilicity” Acta Biomaterialia. 2023, 164, 377–386. Not corresponding author

McClendon, M.; Ji, W.; Greene, A.C.; Sai, H.; Sangji, M. H.; Chen, C.H.; Lee, S.S.; Katchko, K.; Jeong, S.S.; Kannan, A.; Weiner, J.; Cook, R.; Driscoll, A.; Lubbe, R.; Chang. K.; Haleem, M.; Chen, F.; Qiu, R.; Chun, D.; Stock, S.R.; Hsu, W.K.; Hsu, E.L.; Stupp, S.I. “A Supramolecular Polymer-Collagen Microparticle Slurry for Bone Regeneration with Minimal Growth Factor” Biomaterials 2023, 302, 122357. Yuan, S.; Lewis, J.; Sai, H.; Weigand, S.; Palmer, L.; Stupp, S.I. “Peptide Sequence Determines Structural Sensitivity to Supramolecular Polymerization Pathways and Bioactivity” Journal of the American Chemical Society 2022, 144 (36) 16512-16523.

Yuan, S.; Lewis, J.; Sai, H.; Weigand, S.; Palmer, L.; Stupp, S.I. “Peptide Sequence Determines Structural Sensitivity to Supramolecular Polymerization Pathways and Bioactivity” Journal of the American Chemical Society 2022, 144 (36) 16512-16523.

Bruckner, E. P.; Curk, T.; Dordevic, L.; Wang, Z.; Yang, Y.; Qiu, R.; Dannenhoffer, A. J.; Sai, H.; Kupferberg, J.; Palmer, L. C.; Luijten, E.; Stupp, S. I. “Hybrid Nanocrystals of Small Molecules and Chemically Disordered Polymers” ACS Nano 2022, 16 (6), 8993-9003.

Qiu, R.; Sasselli, I. R.; Álvarez, Z.; Sai, H.; Ji, W.; Palmer, L. C.; Stupp, S. I. “Supramolecular Copolymers of Peptides and Lipidated Peptides and their Therapeutic Potential” Journal of the American Chemical Society 2022, 144 (12) 5532-5574.

Bruckner, E.P.; Stupp, S. I. “Designing Supramolecular Polymers with Nucleation and Growth Processes” Polymer International 2022, 71, 590-595.

Aggarwal, A.; Li, C.; Stupp, S. I.; Olvera de la Cruz, M. “Controlling the Shape Morphology of Origami-Inspired Photoresponsive Hydrogels” Soft Matter 2022, 18, 2193-2201.

Dumele, O.; Dordevic, L.; Sai, H.; Cotey, T. J.; Sangji, M. H.; Sato, K.; Dannenhoffer, A. J.; Stupp, S. I. “Photocatalytic Aqueous CO2 Reduction to CO and CH4 Sensitized by Ullazine Supramolecular Polymers” Journal of the American Chemical Society 2022, 144 (7), 3127-3136.

Sasselli, I. R.; Syrgiannis, Z.; Sather, N.; Palmer, L. C; Stupp. S. I.; “Modelling Interactions Within and Between Peptide Amphiphile Supramolecular Filaments” Physical Chemistry B 2022,126(3), 650-659

Stupp, S. I.; Palmer, L. C.; Sai, H. “Crystalline Supramolecular Polymers: Dynamics, Chirality, and Function” Israel Journal of Chemistry 2021, 61(11-12), 873-883

Álvarez, Z.; Edelbrock, A. N.; Sasselli, I. R.; Ortega, J. A.; Syrgiannis, Z.; Mirau, P. A.; Chen, F.; Qiu, R.; Chin, S.M.; Kiskinis, E.; Stupp, S. I. “Bioactive Scaffolds With Enhanced Supramolecular Motion Promote Recovery from Spinal Cord Injury” Science 2021, 374(6569), 848-856. PMCID: PMC8723833

Godbe, J. M; Freeman, R.; Lewis, J. A.; Sasselli, I. R.; Sangji, M. H; Stupp, S. I. “Hydrogen Bonding Stiffens Peptide Amphiphile Supramolecular Filaments by Aza-Glycine Residues” Acta Biomaterialia, 2021, 135, 87-99

Sangji, M. H.; Sai, H.; Chin, S. M.; Lee, S. R.; Sasselli, I. R.; Palmer, L. C.; Stupp, S. I. “Supramolecular Interactions and Morphology of Self-assembling Peptide Amphiphile Nanostructures” Nano Letters 2021, 21(14), 6146-6155.

Jiao, Y.; Dordevic, L.; Mao, H.; Young, R. M.; Jaynes, T.; Chen, H.; Qiu, Y.; Cai, K.; Zhang, L.; Chen, X-Y.; Feng, Y.; Wasielewski, M. R.; Stupp, S. I.; Stoddart, J. F. “A Donor–Acceptor [2] Catenane for Visible Light Photocatalysis” Journal of the American Chemical Society 2021, 143(21), 8000–8010.

Dannenhoffer, A. J.; Sai, H.; Harutyunyan, B.; Narayanan, A.; Powers-Riggs, N. E.; Edelbrock, A. N.; Passarelli, J. V.; Weigand, S. J.; Wasielewski, M. R.; Bedzyk, M. J.; Palmer, L. C.; Stupp, S. I. ”Growth of Extra-Large Chromophore Supramolecular Polymers for

Enhanced Hydrogen Production” Nano Letters 2021 21(9), 3745−3752

Cotey, T. J.; Sai, H.; Perez, C.; Palmer, L.C.; Stupp, S. I. “Hybrid Gels via Bulk Interfacial Complexation of Supramolecular Polymers and Polyelectrolytes” Soft Matter 2021 17, 4949-4956.

Edelbrock, A. N.; Clemons, T. D.; Chin, S. M.; Roan, J. J. W.; Bruckner, E. P.; Álvarez, Z.; Edelbrock, J.; Wek, K. S.; Stupp, S. I. “Superstructured Biomaterials Formed by Exchange Dynamics and Host-Guest Interactions in Supramolecular Polymers” Advanced Science 2021, 8(8): 2004042.

Li, C.; Xue, Y.; Han, M.; Palmer, L. C.; Rogers, J. A.; Huang, Y.; Stupp, S. I. "Synergistic Photoactuation of Bilayered Spiropyran Hydrogels for Predictable Origami-Like Shape Change” Matter 2021, 4(4), 1377-1390.

Li, C.; Lau, G. C.; Yuan, H.; Aggarwal, A.; Dominguez, V. L.; Liu, S.; Sai, H.; Palmer, L. C.; Sather, N. A.; Pearson, T.; Freedman, D.; Amiri, P. K.; Olvera de la Cruz, M.; Stupp, S. I. “Fast and Programmable Locomotion of Hydrogel-Metal Hybrids Under Light and Magnetic Fields” Science Robotics 2020, 5(49), eabb9822.

Clemons, T. D. and Stupp, S. I. “Design of Materials with Supramolecular Polymers” Progress in Polymer Science 2020, 111, 101310.

Chen, C. H.; Hsu, E. L.; Stupp, S. I. “Supramolecular Self-Assembling Peptides to Deliver Bone Morphogenetic Proteins for Skeletal Regeneration” BONE 2020, 141, 115565.

Thames, A.; Wolniak, K.; Stupp, S. I.; Jewett, M. “Principles Learned from the International Race to Develop a Safe and Effective COVID-19 Vaccine” ACS Central Science 2020, 6(8), 1341-1347.

Li, C.; Iscen, A; Sai, H.; Sato, K.; Sather, N. A.; Chin, S.; Àlvarez, Z.; Palmer, L. C.; Schatz, G. C; Stupp, S. I. “Supramolecular-Covalent Hybrid Polymers for Light-Activated Mechanical Actuation” Nature Materials 2020, 19, 900-909.

Passarelli, J. V.; Mauck, C. M.; Winslow, S. W.; Perkinson, C. F.; Bard, J. C.; Sai, H.; Williams, K. W.; Narayanan, A.; Fairfield, D.J.; Hendricks, M. P.; Tisdale, W. A.; Stupp, S. I. “Tunable Exciton Binding Energy in Two-Dimensional Hybrid Layered Perovskites Through Organic-Layer Donor–Acceptor Interactions” Nature Chemistry 2020, 12, 672-682.

Freeman, R.; Han, M.; Álvarez, Z.; Lewis, J. A.; Wester, J. R.; Stephanopoulos, N.; McClendon, M. T.; Lynsky, C.; Godbe, J. M.; Sangji, H.; Luijten E.; Stupp, S. I. "Reversible Self-Assembly of Superstructured Networks" Science 2018, 362 (6416), 808-813.

Lau, G. C.; Sather, N. A.; Sai, H.; Waring, E. M.; Deiss-Yehiely, E.; Barreda. L.; Beeman, E. A.; Palmer, L. C.; Stupp, S. I. “Oriented Multiwalled Organic-Co(OH)₂Nanotubes for Energy Storage” Advanced Functional Materials 2018, 28(3), 1702320.

Hendricks, M. P.; Sato, K.; Palmer, L. C.; Stupp, S. I. "Supramolecular Assembly of Peptide Amphiphiles" Accounts of Chemical Research 2017, 50(10), 2440-2448.

Rubert Pérez, C. M.; Álvarez, Z.; Chen, F.; Aytun, T.; Stupp, S. I. "Mimicking the Bioactivity of Fibroblast Growth Factor-2 using Supramolecular Nanoribbons" ACS Biomater. Sci. Eng. 2017, 3(9), 2166-2175 ACS EDITORS’ CHOICE ARTICLE.

Freeman, R.; Stephanopoulos, N.; Alvarez, Z.; Lewis, J. A.; Sur, S.; Serrano, C. M.; Boekhoven, J.; Lee, S. S.; Stupp, S. I. “Instructing Cells with Programmable Peptide-DNA Hybrids” Nature Communications 2017, 8:15982 doi:10.1038/ncomms15982

Lee. S. S.; Fyrner, T.; Chen, F.; Alvarez, Z.; Sleep, E.; Chun, D. S.; Weiner, J. A.; Cook, R. W.; Freshman, R. D.; Schallmo, M. S.; Katchko, K. M.; Schneider, A. D.; Smith, J. T.; Yun, C.; Singh, G.; Hashmi, S. Z.; McClendon, M. T.; Yu, Z.; Stock, S. R.; Hsu, W. K.; Hsu, E. L.; Stupp, S. I. “Sulfated Glycopeptide Nanostructures for Multipotent Protein Activation” Nature Nanotechnology 2017, 12, 821-829.

Yu, Z.; Tantakitti, F.; Palmer, L.; Stupp, S. I. “Asymmetric Peptide Nanoribbons” Nano Letters 2016, 16(11), 6967-6974.

Tantakitti, F.; Boekhoven, J.; Wang, X.; Kazantsev, R.; Yu, T.; Li, J.; Zhuang, E.; Zandi, R.; Ortony, J. H.; Newcomb, C. J.; Palmer, L. C.; Shekhawat, G. S.; Olvera de la Cruz, M.; Schatz, G. C.; Stupp, S. I. “Energy Landscapes and Function of Supramolecular Systems” Nature Materials 2016, 15(4), 469-476.

Yu, Z; Tantakitti, F.; Yu, T.; Palmer, L. C.; Schatz, G. C.; Stupp, S. I. “Simultaneous Covalent and Non-Covalent Hybrid Polymerizations” Science 2016, 351(6272), 497-502.

Weingarten, A. S.; Kazantsev, R. V.; Palmer, L. C.; Fairfield, D. J.; Koltonow, A. R.; Stupp, S. I. “Supramolecular Packing Controls H₂ Photocatalysis in Chromophore Amphiphile Hydrogels” J. Am. Chem. Soc. 2015, 137(48), 15241-15246. ACS EDITORS’ CHOICE ARTICLE

Tayi, A. S.; Kaeser, A.; Matsumoto, M.; Aida, T.; Stupp, S. I. “Supramolecular Ferroelectrics” Nature Chemistry 2015, 7, 281-294.

Stephanopoulos, N.; Freeman, R.; North, H. A.; Sur, S.; Jeong, S. J.; Tantakitti, F.; Kessler, J, A.; Stupp, S. I. “Bioactive DNA-Peptide Nanotubes Enhance the Differentiation of Neural Stem Cells Into Neurons” Nano Letters 2015, 15(1), 603-609.

Lee, S. S.; Hsu, E. L.; Mendoza, M.; Ghodasra, J.; Nickoli, M. S.; Ashtekar, A.; Polavarapu, M.; Babu, J.; Riaz, R. M.; Nicolas, J. D.; Nelson, D.; Hashmi, S. Z.; Earhart, J. S.; Merk, B. R.; McKee, J. S.; Bairstow, S. F.; Shah, R. N.; Hsu, W. K.; Stupp, S. I. “Gel Scaffolds of BMP-2-binding Peptide Amphiphile Nanofibers for Spinal Arthrodesis” Advanced Healthcare Materials 2015, 4(1), 131-141.

Weingarten, A. S.; Kazantsev, R. V.; Palmer, L. C.; McClendon, M.; Koltonow, A. R.; Samuel, A. P. S.; Kiebala, D. J.; Wasielewski, M. R.; Stupp, S. I. “Self-Assembling Hydrogel Scaffolds for Photocatalytic Hydrogen Production” Nature Chemistry 2014, 6, 964-970.

Cui, H.; Cheetham, A. G.; Pashuck, E. T.; Stupp, S. I. “Amino Acid Sequence in Constitutionally Isomeric Tetrapeptide Amphiphiles Dictates Architecture of One-Dimensional Nanostructures” J. Am. Chem. Soc. 2014, 136(35), 12461-12468.

Preslar, A. T.; Parigi, G.; McCLendon, M. T.; Sefick, S. S.; Moyer, T. J.; Haney, C. R.; Waters, E. A.; MacRenaris, K. W.; Luchinat, C.; Stupp, S. I.; Meade, T. J. “Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization In Vivo” ACS Nano 2014, 8(7), 7325-7332.

Li, A.; Hokugo, A.; Yalom, A.; Berns, E. J.; Stephanopoulos, N.; McClendon, M. T.; Segovia, L. A.; Spigelman, I.; Stupp, S. I.; Jarrahy, R. “A Bioengineered Peripheral Nerve Construct Using Aligned Peptide Amphiphile Nanofibers” Biomaterials 2014, 35(31), 8780-8790.

Ortony, J. H.; Newcomb, C.; Matson, J. B.; Palmer, L. C.; Doan, P. E.; Hoffman, B. M.; Stupp, S. I. “Internal Dynamics of a Supramolecular Nanofiber” Nature Materials 2014, 13, 812-816.

Boekhoven, J.; Stupp, S. I. “Supramolecular Materials for Regenerative Medicine” Advanced Materials 2014, 26(11), 1642-1659.

Newcomb, C. J.; Sur, S.; Ortony, J. H.; Lee, O-S.; Matson, J. B.; Boekhoven, J.; Yu, J-M.; Schatz, G. C.; Stupp, S. I. “ Cell Death Versus Cell Survival Instructed by Supramolecular Cohesion of Nanostructures” Nature Communications 2014, 5(3321), 1-10.

Berns, E. J.; Sur, S.; Pan, L.; Goldberger, J. E.; Suresh, S.; Zhang, S.; Kessler, J. A.; Stupp, S. I. “Aligned Neurite Outgrowth and Directed Cell Migration in Self-Assembled Monodomain Gels” Biomaterials 2014, 35(1), 185-195.

Lee, S. S.; Hunag, B. J.; Kaltz, S. R.; Sur, S.; Newcomb, C. J.; Stock, S. R.; Shah, R. N.; Stupp, S. I. “Bone Regeneration with Low Dose BMP-2 Amplified by Biomimetic Supramolecular Nanofibers within Collagen Scaffolds” Biomaterials 2013, 34(2), 452-459.

Ruff, Y.; Moyer, T.; Newcomb, C. J.; Demeler, B.; Stupp, S.I. “Precision Templating with DNA of a Virus Like Particle with Peptide Nanostructures” JACS 2013, 135(16), 6211-6219.

Boekhoven, J.; Pérez, C. R.; Sur, S.; Worthy, A.; Stupp, S. I.; “Dynamic Display of Bioactivity through Host-Guest Chemistry” Angew. Chem. Int. Ed. 2013,52(46), 12077-12080.

Stephanopoulos, N.; Ortony, J. H.; Stupp, S. I. “Self-Assembly for the Synthesis of Functional Biomaterials” Acta Materialia 2013, 61(3), 912-930.

Zha, R. H.; Sur, S.; Stupp, S. I. “Self-Assembly of Cytotoxic Peptide Amphiphiles into Supramolecular Membranes for Cancer Therapy” Advanced Healthcare Materials 2013, 2(1), 126-133.

Tayi, A. S.; Shveyd, A. K.; Sue, C-H.; Szarko, J. M.; Rolczynski, B. S.; Cao, D.; Kennedy, T. J.; Sarjeant, A. A.; Stern, C. L.; Paxton, W. F.; Wu, W.; Dey, S. K.; Fahrenbach, A. C.; Guest, J. R.; Mohseni, H.; Chen, L. X.; Wang, K. L.; Stoddart, J. F.; Stupp, S. I. “Room-Temperature Ferroelectricity in Supramolecular Networks of Charge-Transfer Complexes” Nature 2012, 488, 485-489.

Aida, T.; Meijer, E. W.; Stupp, S. I. “Functional Supramolecular Polymers” Science 2012, 335(6070), 813-817.

Velichko, Y. S.; Mantei, J. R.; Bitton, R.; Carvajal, D.; Shull, K. R.; Stupp, S. I. “Electric Field Controlled Self-Assembly of Hierarchically Ordered Membranes” Advanced Functional Materials 2012, 22(2), 369-377.

Matson, J.; Stupp, S. I. “Self-Assembling peptide scaffolds for Regenerative Medicine” Chemical Communications 2012, 48(1), 26-33.

Tevis, I. D.; Palmer, L. C.; Herman, D. J.; Murray, I. P.; Stone, D. A.; Stupp, S. I. “Self-Assembly and Orientation of Hydrogen-Bonded Oligothiophene Polymorphs at Liquid-Membrane-Liquid Interfaces” J. Am. Chem. Soc. 2011, 133(41), 16486-16494.

Goldberger, J. E.; Berns, E. J.; Bitton, R.; Newcomb, C. J.; Stupp, S. I. “Electrostatic Control of Bioactivity” Angew. Chem. Int. Ed. 2011, 50(28), 6292-6295.

Rożkiewicz, D. I.; Myers, B. D.; Stupp, S. I. “Interfacial Self-Assembly of Cell-like Filamentous Microcapsules” Angew. Chem. Int. Ed. 2011, 50(28), 6324-6327.

Webber, M. J.; Tongers, J.; Newcomb, C. J.; Marquardt, K-T.; Bauersachs, J.; Losordo, D. W.; Stupp, S. I. “Supramolecular Nanostructures that Mimic VEGF as a strategy for Ischemic Tissue Repair” Proc. Natl. Acad. Sci. 2011, 108(33), 13438-13443.

Huang, Z.; Newcomb, C. J.; Bringas, P.; Stupp, S. I.; Snead, M. L. “Biological Synthesis of Tooth Enamel Instructed by an Artificial Matrix” Biomaterials 2010, 31(35), 9202-9211.

Stupp, S. I. “Self-Assembly and Biomaterials” Nano Letters 2010, 10(12), 4783-4786.

Shah, R. M.; Shah, N. A.; Del Rosario Lim, M. M.; Hsieh, C.; Nuber, G.; Stupp, S. I. “Supramolecular Design of Self-Assembling Nanofibers for Cartilage Regeneration” Proc. Natl. Acad. Sci. 2010, 107(8), 3293-3298.

Mata, A.; Geng, Y.; Henrikson, K.; Aparicio, C.; Stock, S.; Satcher, R. L.; Stupp, S. I. “Bone Regeneration Mediated by Biomimetic Mineralization of a Nanofiber Matrix” Biomaterials 2010, 31(23), 6004-6012.

Pashuck, E. T.; Cui, H.; Stupp, S. I. “Tuning Supramolecular Rigidity of Peptide Fibers through Molecular Structure”J. Am. Chem. Soc. 2010, 132(17), 6041-6046.

Zhang, S.; Greenfield, M. A.; Mata, A.; Palmer, L. C.; Bitton, R.; Mantei, J. R.; Aparicio, C.; Olvera de la Cruz, M.; Stupp, S. I. “A Self-Assembly Pathway to Aligned Monodomain Gels” Nature Materials 2010, 9(7), 594-601.

Cui, H.; Pashuck, E. T.; Velichko, Y. S.; Weigand, S. J.; Cheetham, A. G.; Newcomb, C. J.; Stupp, S. I. “Spontaneous and X-Ray Triggered Crystallization at Long Range in Self-Assembling Filament Networks” Science 2010, 327(5965), 555-559.

Sofos, M.; Goldberger, J.; Stone, D. A.; Allen, J. E.; Ma, Q.; Herman, D. J.; Tsai. W-W.; Lauhon, L. J.; Stupp. S. I. “A Synergistic Assembly of Nanoscale Lamellar Photoconductor Hybrids” Nature Materials 2009, 8(1), 68-75.

Faculty DirectorySamuel Stupp