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BME 371: Mechanics of Biological Tissues

This course is not currently offered.

Prerequisites

GEN ENG 205-3,4; BME 271

Description

This course covers the fundamentals of continuum mechanics and constitutive modeling relevant for soft biological tissues. Constitutive models covered include nonlinear elasticity and viscoelasticity. If time permits, an introductory poroelasticity will be presented. Structure-function relationships which link tissue morphology and physiology to tissue constitutive models will be covered for ligaments, muscles, skin, and nervous tissues.

Who Takes It

BME juniors, seniors, and first year graduate students

Mini-Syllabus

Index Notation, Vectors, and Tensors
Continuum Mechanics Concepts of Stress, Strain and Momentum Balance
Determination of Boundary Conditions
Constitutive Models Using Strain Energy : Nonlinear Elasticity and Viscoelasticity
Skeletal Soft Tissue (cartilage, ligament/tendon, muscle) Structure-Function
Skin, Nerve Structure-Function
Strain energy representation of soft tissues constitutive models
Experimental paradigms used to identify mechanical properties of soft tissues
Procedures for estimating material coefficients

Textbook

1) Web-based notes provided by Instructor

2) Text Books on the reference desk in the engineering library:

Nonlinear Solid Mechanics : A Continuum Approach for Engineering Gerhard A. Holzapfel Graz University of Technology, Austria
Continuum Mechanics for Engineers, Second Edition George E. Mase Michigan State University, East Lansing, Michigan, USA G. Thomas Mase Michigan State University, East Lansing, Michigan USA
Nonlinear Theory of Elasticity Applications in Biomechanics Larry A Taber Washington University, USA
Biomechanics: Mechanical Properties of Living Tissues, Second Edition Yuan-Cheng Fung University of California San Diego, USA