News & Events / BME Seminar Series / Current Speakers / 2020-21Warren Grayson, PhD
Open BME Seminar Series
Thursday, March 25th, 2021 at 3-4 pm CST
Host: Professor Guillermo Ameer
Professor and Vice-Chair for Faculty Affairs in Biomedical Engineering
Joint Appointments: Materials Science & Engineering, Chemical & Biomolecular Engineering
Translational Tissue Engineering Center
Institute for Nanobiotechnology
Johns Hopkins University School of Medicine
Advances in Regenerating Musculoskeletal Tissues
Tissue engineering provides a viable means of regenerating bone and skeletal muscle tissues following injuries that lead to large volumetric defects. Our lab has developed advanced biomaterial and stem cell-based approaches to promote functional recovery following volumetric muscle loss and critical-sized craniofacial bone injuries. This presentation will focus on three areas of ongoing research: (1) I will present our lab’s efforts to regenerate vascularized and innervated skeletal muscle in mice including our recent studies using human pluripotent stem cells. (2) Recently, our group completed a study focused on designing biomaterials to guide bone regeneration in situ in minipigs using intraoperative protocols for combining autologous stem cells with 3D-printed scaffolds. (3) Understanding the interaction between vascular cells and osteoprogenitors is critical for developing effective treatment methods. I will describe recent studies in which we developed a quantitative imaging platform for characterizing the spatial relationships between cell populations in the native murine calvarium.
Learn more about Dr. Warren Grayson and their research here.